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Reference: Halliday, A and Norris, JW, (2010). Carotid artery stenosis. The BMJ, 340, c748.Citable link to this page:


Carotid artery stenosis

Abstract: Carotid endarterectomy is currently the most effective intervention to prevent stroke in patients with recent symptoms of carotid stenosis.1 2 It also prevents future stroke in younger patients (under 75 years) who have not yet had symptoms, as long as the risk of stroke and death from surgery is not more than 3%Patients naturally prefer carotid artery stenting to open surgery, but stenting has not been shown to be acceptably safe in clinical trials. Carotid endarterectomy has been in widespread use for more than 50 years, but carotid artery stenting is a more recent development. In the linked systematic review (doi:10.1136/bmj.c467), Meier and colleagues assessed the short term safety and intermediate term efficacy of carotid endarterectomy versus carotid artery stenting. They found that the short term (30 day) hazards of stroke and death after stenting in recent trials of symptomatic patients have improved but are not yet as good as those seen after surgery.5 In the intermediate term, the two treatments did not differ significantly for stroke or death (hazard ratio 0.90, 95% confidence interval 0.74 to 1.1).

Peer Review status:Peer reviewedPublication status:PublishedVersion:Accepted manuscriptNotes:© 2010 Halliday and Norris

Bibliographic Details

Publisher: BMJ Publishing Group

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Journal: The BMJsee more from them

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Issue Date: 2010-02

Article Number:ARTN c748


Urn: uuid:515a5666-5ec0-4331-a3c7-9eaafca315d2

Source identifier: 309121

Eissn: 1756-1833


Issn: 0959-8138 Item Description

Type: Journal article;

Language: eng

Version: Accepted manuscriptKeywords: Humans Carotid Stenosis Myocardial Infarction Endarterectomy, Carotid Stents Stroke Tiny URL: pubs:309121


Autor: Halliday, A - institutionUniversity of Oxford Oxford, MSD, Surgical Sciences - - - Norris, JW - - - - Bibliographic Details Publi



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