A comparison of risk factors for mortality from heart failure in Asian and non-Asian populations: an overview of individual participant data from 32 prospective cohorts from the Asia-Pacific Region.Reportar como inadecuado




A comparison of risk factors for mortality from heart failure in Asian and non-Asian populations: an overview of individual participant data from 32 prospective cohorts from the Asia-Pacific Region. - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Reference: Huxley, RR, Barzi, F, Woo, J et al., (2014). A comparison of risk factors for mortality from heart failure in Asian and non-Asian populations: an overview of individual participant data from 32 prospective cohorts from the Asia-Pacific Region. BMC cardiovascular disorders, 14 (1), 61.Citable link to this page:

 

A comparison of risk factors for mortality from heart failure in Asian and non-Asian populations: an overview of individual participant data from 32 prospective cohorts from the Asia-Pacific Region.

Abstract: BACKGROUND: Most of what is known regarding the epidemiology of mortality from heart failure (HF) comes from studies within Western populations with few data available from the Asia-Pacific region where the burden of heart failure is increasing. METHODS: Individual level data from 543694 (85% Asian; 36% female) participants from 32 cohorts in the Asia Pacific Cohort Studies Collaboration were included in the analysis. Adjusted hazard ratios (HR) and 95% confidence intervals (CI) for mortality from HF were estimated separately for Asians and non-Asians for a quintet of cardiovascular risk factors: systolic blood pressure, diabetes, body mass index, cigarette smoking and total cholesterol. All analyses were stratified by sex and study. RESULTS: During 3,793,229 person years of follow-up there were 614 HF deaths (80% Asian). The positive associations between elevated blood pressure, obesity, and cigarette smoking were consistent for Asians and non-Asians. There was evidence to indicate that diabetes was a weaker risk factor for death from HF for Asians compared with non-Asians: HR 1.26 (95% CI: 0.74-2.13) versus 3.04 (95% CI 1.76-5.25) respectively; p for interaction = 0.022. Additional adjustment for covariates did not materially change the overall associations. There was no good evidence to indicate that total cholesterol was a risk factor for HF mortality in either population. CONCLUSIONS: Most traditional cardiovascular risk factors including elevated blood pressure, obesity and cigarette smoking appear to operate similarly to increase the risk of death from HF in Asians and non-Asians populations alike.

Peer Review status:Peer reviewedPublication status:PublishedVersion:Publisher's version Funder: Australian National Health and Medical Research Council   Notes:© 2014 Huxley et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Contributors

Norton, RMore by this contributor

RoleCollaborator

 

Whitlock, GMore by this contributor

RoleCollaborator

 Bibliographic Details

Publisher: BioMed Central Ltd.

Publisher Website: http://www.biomedcentral.com/

Publisher: BioMed Central Ltd.

Journal: BMC cardiovascular disorderssee more from them

Publication Website: http://www.biomedcentral.com/bmccardiovascdisord/

Issue Date: 2014-05-03

pages:61Identifiers

Urn: uuid:a0cbdb60-d444-44a0-856b-58873ba1e261

Source identifier: 469891

Eissn: 1471-2261

Doi: https://doi.org/10.1186/1471-2261-14-61

Issn: 1471-2261 Item Description

Type: Journal article;

Language: eng

Version: Publisher's versionKeywords: Meta-analysis Heart failure EpidemiologySubjects: Asia Cardiovascular disease Epidemiology Tiny URL: pubs:469891

Relationships





Autor: Huxley, RR - - - Barzi, F - - - Woo, J - - - Giles, G - - - Lam, TH - - - Rahimi, K - institutionUniversity of Oxford facultyMedi

Fuente: https://ora.ox.ac.uk/objects/uuid:a0cbdb60-d444-44a0-856b-58873ba1e261



DESCARGAR PDF




Documentos relacionados