Weight loss referrals for adults in primary care WRAP: protocol for a multi-centre randomised controlled trial comparing the clinical and cost-effectiveness of primary care referral to a commercial weight loss provider for 12 weeReport as inadecuate




Weight loss referrals for adults in primary care WRAP: protocol for a multi-centre randomised controlled trial comparing the clinical and cost-effectiveness of primary care referral to a commercial weight loss provider for 12 wee - Download this document for free, or read online. Document in PDF available to download.

Reference: Ahern, AL, Aveyard, PN, Halford, JC et al., (2014). Weight loss referrals for adults in primary care (WRAP): protocol for a multi-centre randomised controlled trial comparing the clinical and cost-effectiveness of primary care referral to a commercial weight loss provider for 12 weeks, referral for 52 weeks, and a brief self-help intervention [ISRCTN82857232]. BMC public health, 14 (1), 620.Citable link to this page:

 

Weight loss referrals for adults in primary care (WRAP): protocol for a multi-centre randomised controlled trial comparing the clinical and cost-effectiveness of primary care referral to a commercial weight loss provider for 12 weeks, referral for 52 weeks, and a brief self-help intervention [ISRCTN82857232].

Abstract: BACKGROUND: Recent trials demonstrate the acceptability and short term efficacy of primary care referral to a commercial weight loss provider for weight management. Commissioners now need information on the optimal duration of intervention and the longer term outcomes and cost effectiveness of such treatment to give best value for money. METHODS/DESIGN: This multicentre, randomised controlled trial with a parallel design will recruit 1200 overweight adults (BMI ≥28 kg/m2) through their primary care provider. They will be randomised in a 2:5:5 allocation to: Brief Intervention, Commercial Programme for 12 weeks, or Commercial Programme for 52 weeks. Participants will be followed up for two years, with assessments at 0, 3, 12 and 24 months. The sequential primary research questions are whether the CP interventions achieve significantly greater weight loss from baseline to 12 months than BI, and whether CP52 achieves significantly greater weight loss from baseline to 12 months than CP12. The primary outcomes will be an intention to treat analysis of between treatment differences in body weight at 12 months. Clinical effectiveness will be also be assessed by measures of weight, fat mass, and blood pressure at each time point and biochemical risk factors at 12 months. Self-report questionnaires will collect data on psychosocial factors associated with adherence, weight-loss and weight-loss maintenance. A within-trial and long-term cost-effectiveness analysis will be conducted from an NHS perspective. Qualitative methods will be used to examine the participant experience. DISCUSSION: The current trial compares the clinical and cost effectiveness of referral to a commercial provider with a brief intervention. This trial will specifically examine whether providing longer weight-loss treatment without altering content or intensity (12 months commercial referral vs. 12 weeks) leads to greater weight loss at one year and is sustained at 2 years. It will also evaluate the relative cost-effectiveness of the three interventions. This study has direct implications for primary care practice in the UK and will provide important information to inform the decisions of practitioners and commissioners about service provision. TRIAL REGISTRATION: Current Controlled Trials ISRCTN82857232. Date registered: 15/10/2012.

Peer Review status:Peer reviewedPublication status:PublishedVersion:Publisher version Funder: National Institute for Health Research   Funder: Medical Research Council   Notes:Copyright 2014 Ahern et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Bibliographic Details

Publisher: BioMed Central Ltd

Publisher Website: http://www.biomedcentral.com/

Publisher: BioMed Central Ltd.

Journal: BMC public healthsee more from them

Publication Website: http://www.biomedcentral.com/bmcpublichealth

Issue Date: 2014

pages:620Identifiers

Urn: uuid:f9b112c9-dda1-4e47-b062-869163f2cf53

Source identifier: 480823

Eissn: 1471-2458

Doi: https://doi.org/10.1186/1471-2458-14-620

Issn: 1471-2458 Item Description

Type: Journal article;

Language: eng

Version: Publisher versionKeywords: obesity weight-loss primary care adults Tiny URL: pubs:480823

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Author: Ahern, AL - - - Aveyard, PN - institutionUniversity of Oxford Oxford, MSD, Primary Care Health Services - - - Halford, JC - - - M

Source: https://ora.ox.ac.uk/objects/uuid:f9b112c9-dda1-4e47-b062-869163f2cf53



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