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Reference: Kolasinski, James, Makin, TR, Logan, JP et al., (2016). Perceptually relevant remapping of human somatotopy in 24 hours. eLife.Citable link to this page:

 

Perceptually relevant remapping of human somatotopy in 24 hours.

Abstract: Experience-dependent reorganisation of functional maps in the cerebral cortex is well described in the primary sensory cortices. However, there is relatively little evidence for such cortical reorganisation over the short-term. Using human somatosensory cortex as a model, we investigated the effects of a 24-hour gluing manipulation in which the right index and right middle fingers (digits 2 and 3) were adjoined with surgical glue. Somatotopic representations, assessed with two 7 tesla fMRI protocols, revealed rapid off-target reorganisation in the non-manipulated fingers following gluing, with the representation of the ring finger (digit 4) shifted towards the little finger (digit 5) and away from the middle finger (digit 3). These shifts were also evident in two behavioural tasks conducted in an independent cohort, showing reduced sensitivity for discriminating the temporal order of stimuli to the ring and little fingers, and increased substitution errors across this pair on a speeded reaction time task.

Publication status:PublishedPeer Review status:Peer reviewedVersion:Accepted manuscriptDate of acceptance:2016-12-29 Funder: National Institute for Health Research   Funder: Medical Research Council   Notes:© 2016, Kolasinski et al. This article is distributed under the terms of the Creative Commons Attribution License permitting unrestricted use and redistribution provided that the original author and source are credited.

Bibliographic Details

Publisher: eLife

Publisher Website: https://elifesciences.org/

Journal: eLifesee more from them

Publication Website: https://elifesciences.org/

Volume: 5

Issue Date: 2016-12Identifiers

Doi: https://doi.org/10.7554/eLife.17280

Issn: 2050-084X

Uuid: uuid:68a72f62-1fce-4a9d-a4f8-e59bbb925ba3

Urn: uri:68a72f62-1fce-4a9d-a4f8-e59bbb925ba3

Pubs-id: pubs:667710 Item Description

Type: journal-article;

Language: eng

Version: Accepted manuscriptKeywords: human neuroscience

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Autor: Kolasinski, James - Oxford, MSD, Clinical Neurosciences University College fundingUniversity College, Oxford grantNumberStevenson

Fuente: https://ora.ox.ac.uk/objects/uuid:68a72f62-1fce-4a9d-a4f8-e59bbb925ba3



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