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Reference: Vidaurre, D, Abeysuriya, R, Becker, R et al., (2017). Discovering dynamic brain networks from big data in rest and task. NeuroImage.Citable link to this page:

 

Discovering dynamic brain networks from big data in rest and task

Abstract: Brain activity is a dynamic combination of the responses to sensory inputs and its own spontaneous processing. Consequently, such brain activity is continuously changing whether or not one is focusing on an externally imposed task. Previously, we have introduced an analysis method that allows us, using Hidden Markov Models (HMM), to model task or rest brain activity as a dynamic sequence of distinct brain networks, overcoming many of the limitations posed by sliding window approaches. Here, we present an advance that enables the HMM to handle very large amounts of data, making possible the inference of very reproducible and interpretable dynamic brain networks in a range of different datasets, including task, rest, MEG and fMRI, with potentially thousands of subjects. We anticipate that the generation of large and publicly available datasets from initiatives such as the Human Connectome Project and UK Biobank, in combination with computational methods that can work at this scale, will bring a breakthrough in our understanding of brain function in both health and disease.

Publication status:In pressPeer Review status:Peer reviewedVersion:Publisher's versionNotes:Crown Copyright © 2017 Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Bibliographic Details

Publisher: Elsevier

Publisher Website: http://www.elsevier.com/

Journal: NeuroImagesee more from them

Publication Website: https://www.journals.elsevier.com/neuroimage

Issue Date: 29 June 2017Identifiers

Doi: https://doi.org/10.1016/j.neuroimage.2017.06.077

Issn: 1053-8119

Uuid: uuid:86678704-f293-4a95-a392-5922b259cdad

Urn: uri:86678704-f293-4a95-a392-5922b259cdad

Pubs-id: pubs:707823 Item Description

Type: journal-article;

Language: eng

Version: Publisher's versionKeywords: Journal Article Review

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Autor: Vidaurre, D - Oxford, MSD, Psychiatry St Edmund Hall fundingWellcome Trust grantNumberStrategic Award 098369-Z-12-Z - - - Abeysur

Fuente: https://ora.ox.ac.uk/objects/uuid:86678704-f293-4a95-a392-5922b259cdad



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