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(2006)GENOME BIOLOGY.7(5). Mark abstract ReMoDiscovery' is an intuitive algorithm to correlate regulatory programs with regulators and corresponding motifs to a set of co-expressed genes. It exploits in a concurrent way three independent data sources: ChIP-chip data, motif information and gene expression profiles. When compared to published module discovery algorithms, ReMoDiscovery is fast and easily tunable. We evaluated our method on yeast data, where it was shown to generate biologically meaningful findings and allowed the prediction of potential novel roles of transcriptional regulators.

Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-3186959



Autor: Karen Lemmens, Thomas Dhollander, Tijl De Bie , Pieter Monsieurs, Kristof Engelen, Bart Smets, Joris Winderickx, Bart De Moor and

Fuente: https://biblio.ugent.be/publication/3186959



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