Prevention of central line-associated bloodstream infections through quality improvement interventions: a systematic review and meta-analysisReportar como inadecuado




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(2014)CLINICAL INFECTIOUS DISEASES.59(1).p.96-105 Mark abstract This systematic review and meta-analysis examines the impact of quality improvement interventions on central line-associated bloodstream infections in adult intensive care units. Studies were identified through Medline and manual searches (1995-June 2012). Random-effects meta-analysis obtained pooled odds ratios (ORs) and 95% confidence intervals (CIs). Meta-regression assessed the impact of bundle/checklist interventions and high baseline rates on intervention effect. Forty-one before-after studies identified an infection rate decrease (OR, 0.39 [95% CI,.33-.46]; P <.001). This effect was more pronounced for trials implementing a bundle or checklist approach (P = .03). Furthermore, meta-analysis of 6 interrupted time series studies revealed an infection rate reduction 3 months postintervention (OR, 0.30 [95% CI,.10-.88]; P = .03). There was no difference in infection rates between studies with low or high baseline rates (P = .18). These results suggest that quality improvement interventions contribute to the prevention of central line-associated bloodstream infections. Implementation of care bundles and checklists appears to yield stronger risk reductions.

Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-4240026



Autor: Koen Blot, Jochen Bergs, Dirk Vogelaers , Stijn Blot and Dominique Vandijck

Fuente: https://biblio.ugent.be/publication/4240026



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