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 Verongamine, a novel bromotyrosine derived histamine H3-antagonist from the marine sponge Verongula gigantea.


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Type of Resource: text

Genre: article

Issuance: single unit

Date Issued: 1994

Publisher: American Chemical Society

Extent: 4 p.

Physical Description: pdf

Language(s): English

Identifier: 3318974 (digitool), FADT3318974 (IID), fau:6024 (fedora)

Note(s): The novel bromotyrosine derivative verongamine [1] has been isolated from the marine sponge Verongula gigantea. The isolation of verongamine was facilitated by employing histamine-H3 bioassay-guided fractionation. Verongamine is a specific histamine-H3 antagonist at concentrations as low as 1 microgram/ml.This document is the accepted manuscript version of a published work that appeared in final form in Journal of Natural Products after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np50103a029. This article may be cited as: Mierzwa, R., King, A., Conover, M. A., Tozzi, S., Puar, M. S., Patel, M., Coval, S. J., & Pomponi, S. A. (1994). Verongamine, a novel bromotyrosine derived histamine H3-antagonist from the marine sponge Verongula gigantea. Journal of Natural Products, 57(1), 175-177. doi:10.1021/np50103a029Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #993.

Subject(s): Sponges --ResearchMarine natural productsDrug Discovery

Persistent Link to This Record: http://purl.flvc.org/FCLA/DT/3318974

Links: http://dx.doi.org/10.1021/np50103a029

Restrictions on Access: ©1994 American Chemical Society

Owner Institution: FAU



Autor: Mierzwa, R., creator King, A., creator Conover, M.A., creator Tozzi, S., creator Puar, M. S., creator Patel, M., creator Coval, S

Fuente: http://fau.digital.flvc.org/islandora/object/fau%3A6024



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