Using C. elegans as a Model System to Discover Antiepileptic Drugs.
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Type of Resource: text
Genre: thesis
Date Created: Spring 2016
Date Issued: 2016
Publisher: Florida Atlantic University
Place of Publication: Boca Raton, Florida
Physical Form: pdf
Extent: 21 p.
Language(s): English
Abstract/Description: Novel antiepileptic drugs (AEDs) are commonly tested using rats and mice as model systems. These animals, however, require a great deal of time, money, and lab space to maintain. In contrast, the nematode Caenorhabditis elegans (C. elegans) potentially can provide a faster, and less expensive model system for testing AEDs. C. elegans are simple to maintain and have a very short generation time, allowing high throughput assays to screen for new AEDs. For my thesis research, I used C. elegans to test FDA approved AEDs. My tests support the contention that C. elegans can be a useful model system for AED discovery.
Identifier: FA00003682 (IID)
Note(s): Includes bibliography.Thesis (B.A.)--Florida Atlantic University, Harriet L. Wilkes Honors College, 2016.
Held by: Florida Atlantic University Libraries
Sublocation: Digital Library
Persistent Link to This Record: http://purl.flvc.org/fau/fd/FA00003682
Restrictions on Access: All rights reserved by the source institution
Owner Institution: FAU
Autor: Merritt, Mckenzie D. Wetterer, James Dr. Harriet L. Wilkes Honors College
Fuente: http://fau.digital.flvc.org/islandora/object/fau%3A33792