Microxine, a New cdc2 Kinase Inhibitor from the Australian MarinE Sponge Microxina Species.Reportar como inadecuado


 Microxine, a New cdc2 Kinase Inhibitor from the Australian MarinE Sponge Microxina Species.


Microxine, a New cdc2 Kinase Inhibitor from the Australian MarinE Sponge Microxina Species. - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.



Type of Resource: text

Genre: article

Issuance: single unit

Date Issued: 2001

Publisher: American Chemical Society and American Society of Pharmacognosy

Extent: 3 p.

Physical Description: pdf

Language(s): English

Identifier: 3164092 (digitool), FADT3164092 (IID), fau:5604 (fedora)

Note(s): A new purine derivative microxine (1) was isolated from the Australian marine sponge Microxina sp. The compound was isolated via reversed-phase chromatography and its structure determined spectroscopically. Microxine was found to weakly inhibit cdc2 kinase activity with an IC50 of 13 µM.This document is the accepted manuscript version of a published work that appeared in final form in Journal of Natural Products after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np000546z. This article may be cited as: Killday, K. B., Yarwood, D., Sills, M. A., Murphy, P. T., Hooper, J. N. A., & Wright, A. E. (2001). Microxine, a New cdc2 Kinase Inhibitor from the Australian Marine Sponge Microxina Species. Journal of Natural Products, 64(4), 525-526.Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #1400.

Subject(s): SpongesChromatographic analysisSpectrum analysisPhosphoprotein Phosphatase --analysisNucleosides

Persistent Link to This Record: http://purl.flvc.org/FCLA/DT/3164092

Links: http://dx.doi.org/10.1021/np000546z

Restrictions on Access: ©2001 American Chemical Society and American Society of Pharmacognosy.

Owner Institution: FAU



Autor: Killday, K. Brian, creator Yarwood, Donna, creator Sills, Matthew A., creator Murphy, Peter T., creator Hooper, J. N. A., creator

Fuente: http://fau.digital.flvc.org/islandora/object/fau%3A5604



DESCARGAR PDF




Documentos relacionados