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Jorge A. Pinto ; Laura J. Melo ; Mariana A. Vasconcelos ; Rafael de Matos Pereira ;Jornal de Pediatria 2006, 82 4

Autor: Roberta M. C. Romanelli

Fuente: http://www.redalyc.org/articulo.oa?id=399738113006


Introducción



Jornal de Pediatria ISSN: 0021-7557 assessoria@jped.com.br Sociedade Brasileira de Pediatria Brasil Romanelli, Roberta M.
C.; Pinto, Jorge A.; Melo, Laura J.; Vasconcelos, Mariana A.; de Matos Pereira, Rafael Effectiveness of dual and triple antiretroviral therapy in the treatment of HIV-infected children Jornal de Pediatria, vol.
82, núm.
4, julio-agosto, 2006, pp.
260-265 Sociedade Brasileira de Pediatria Porto Alegre, Brasil Available in: http:--www.redalyc.org-articulo.oa?id=399738113006 How to cite Complete issue More information about this article Journals homepage in redalyc.org Scientific Information System Network of Scientific Journals from Latin America, the Caribbean, Spain and Portugal Non-profit academic project, developed under the open access initiative 0021-7557-06-82-04-260 Jornal de Pediatria Copyright © 2006 by Sociedade Brasileira de Pediatria doi:10.2223-JPED.1505 ORIGINAL ARTICLE Effectiveness of dual and triple antiretroviral therapy in the treatment of HIV-infected children Roberta M.
C.
Romanelli,1 Jorge A.
Pinto,2 Laura J.
Melo,3 Mariana A.
Vasconcelos,4 Rafael de Matos Pereira5 Abstract Objective: The use of antiretroviral therapy in HIV-infected children has been a widely discussed issue.
The aim of this study was to compare the effectiveness of dual nucleoside analogue reverse transcriptase inhibitor (NRTI) regimens and three-drug regimens [2NRTI non-nucleoside reverse transcriptase inhibitor (NNRTI) or protease inhibitor (PI)] in a cohort of HIV-infected children. Methods: The study was carried out in a referral center for the management of infected children, which is affiliated with the School of Medicine of Universidade Federal de Minas Gerais (UFMG).
Those children whose antiretroviral therapy was implemented between January 1998 and December 2000 and who were followed until December 2001 were included in the study.
Therapeutic failure or death was regarded as the endpoint in our analysis. Results: A total of 101 patien...





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