Chemical constituents, antibacterial and antioxidant properties of the essential oil flower of Tagetes minuta grown in Cala community Eastern Cape, South AfricaReportar como inadecuado




Chemical constituents, antibacterial and antioxidant properties of the essential oil flower of Tagetes minuta grown in Cala community Eastern Cape, South Africa - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

BMC Complementary and Alternative Medicine

, 17:351

Basic research

Abstract

BackgroundTagetes minuta has a long record of human use for the treatment of stomach and intestinal diseases. Most drugs used for diseases treatment are less efficacious with side effects and this brought the search for new treatment regimens mainly from medicinal plants.

MethodThe essential oil EO was extracted by Clevenger’s-type apparatus and its chemical composition, antioxidant and antibacterial properties were determined by GC-MS, spectrophotometric and broth dilution methods respectively. S. uberis, E. cloacae, S. aureus, M. smegmatis, L. ivanovii, Vibrio spp. and E. coli bacteria strains were used as test bacteria.

ResultsGC-MS analysis revealed 98 compounds in the EO flower of T. minuta and β-Ocimene 14. 40% was the major chemical constituents. The EO exhibited highest inhibitory effect against DPPH radical, followed by its effect on ABTS, while LP radical showed the least sensitivity with IC50 values of 2.45 mg-mL, 2.76 mg-mL and 3.23 mg-mL respectively. The EO showed antibacterial activities against all test organisms with MIC value for S. aureus, M. smegatis and S. uberis at 0.125 mg-mL and for L. ivanovii, Vibrio spp., E. cloacae and E. coli at 0.06 mg-mL. The EO showed MBC against E. cloacae and E. coli at 0.06 mg-mL at 0.5 mg-mL for S. uberis and 0.125 mg-mL for Vibrio spp.

ConclusionFindings from this study suggest that the EO of T. minuta flower may be a useful candidate in the search for lead constituents for the synthesis of new potent antibacterial and antioxidant agent.

KeywordsAntibacterial Antioxidant Tegates minuta Vitamin C  Download fulltext PDF



Autor: Aboi Igwaran - Benson Chucks Iweriebor - Sunday Ofuzim Okoh - Uchechukwu Uchechukwu Nwodo - Larry Chikwelu Obi - Anthony 

Fuente: https://link.springer.com/







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