Carotid plaque rather than intima-media thickness as a predictor of recurrent vascular events in patients with acute ischemic strokeReportar como inadecuado




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Cardiovascular Ultrasound

, 15:19

First Online: 24 July 2017Received: 11 May 2017Accepted: 13 July 2017

Abstract

BackgroundTo investigate the impacts of carotid plaque and intima-media thickness IMT on future vascular events VEs in the patients with acute ischemic stroke.

MethodsA total of 479 consecutive Korean patients with acute ischemic stroke were divided into 2 groups according to development of VEs; VE group 65.4 ± 10.9 years vs no VE group 62.8 ± 13.2 years. VEs were defined as the development of recurrent stroke, coronary events, peripheral arterial disease, and death. Clinical, laboratory, and imaging findings were compared between the groups.

ResultsDuring 105.5 ± 29.0 months of follow up, VEs were developed in 142 patients 29.6%. In univariate analysis, VEs were significantly associated with age, gender, diabetes, renal function, lipid levels, left ventricular function, carotid plaque or IMT. In multivariate analysis, the presence of carotid plaque, diabetes, renal function and male gender were independent predictors of future VEs in the patients with ischemic stroke, but carotid IMT was not a predictor of future VEs. Event free survival was significantly lower in patients with carotid plaque than without carotid plaque on Kaplan-Meier analysis log rank p < 0.001.

ConclusionThe present study demonstrated that diabetes, impaired renal function, male gender, and the presence of carotid plaque rather than IMT were independent predictors of future VEs in Korean patients with acute ischemic stroke. Active medical management and careful monitoring for the development of recurrent VEs are strongly recommended in patients with acute ischemic stroke and carotid plaque.

KeywordsCarotid artery Plaque Intima-media thickness Stroke  Download fulltext PDF



Autor: Hyun Ju Yoon - Kye Hun Kim - Hyukjin Park - Jae Yeong Cho - Young Joon Hong - Hyung Wook Park - Ju Han Kim - Youngkeu

Fuente: https://link.springer.com/







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