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World Journal of Emergency Surgery

, 11:51

First Online: 11 October 2016Received: 18 August 2016Accepted: 29 September 2016


BackgroundNecrotizing fasciitis is an uncommon, rapidly progressive and potential lethal condition. Over the last decade time to surgery decreased and outcome improved, most likely due to increased awareness and more timely referral. Early recognition is key to improve mortality and morbidity. However, early referral frequently makes it a challenge to recognize this heterogeneous disease in its initial stages. Signs and symptoms might be misleading or absent, while the most prominent skin marks might be in discrepancy with the position of the fascial necrosis. Gram staining and especially fresh frozen section histology might be a useful adjunct.

MethodsRetrospective analysis of 3 year period. Non-transferred patients who presented with suspected necrotizing fasciitis are included. ASA classification was determined. Mortality was documented.

ResultsIn total, 21 patients are included. Most patients suffered from severe comorbidities. In 11 patients, diagnoses was confirmed based on intra-operative macroscopic findings. Histology and-or microbiotic findings resulted in 6-10 remaining patients in a change in treatment strategy. In total, 17 patients proved to suffer necrotizing fasciitis. In the cohort series 2 patients died due to necrotizing fasciitis

ConclusionIn the early phases of necrotizing fasciitis, clinical presentation can be ambivalent. In the present cohort, triple diagnostics consisting of an incisional biopsy with macroscopic, histologic and microbiotic findings was helpful in timely identification of necrotizing fasciitis.

KeywordsNecrotizing fasciitis Early recognition Triple diagnostics Histology Fresh frozen section  Download fulltext PDF

Autor: Falco Hietbrink - Lonneke G. Bode - Louis Riddez - Luke P. H. Leenen - Marijke R. van Dijk


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