E. coli bacteremia in comparison to K. pneumoniae bacteremia: influence of pathogen species and ESBL production on 7-day mortalityReport as inadecuate




E. coli bacteremia in comparison to K. pneumoniae bacteremia: influence of pathogen species and ESBL production on 7-day mortality - Download this document for free, or read online. Document in PDF available to download.

Antimicrobial Resistance and Infection Control

, 5:37

First Online: 19 October 2016Received: 30 May 2016Accepted: 03 October 2016

Abstract

In a previous study, we demonstrated prolonged length of hospital stay in cases of extended-spectrum beta-lactamase ESBL-positive K. pneumoniae bacteremia compared to bacteremia cases due to E. coli ESBL-positive and –negative and ESBL-negative K. pneumoniae. The overall mortality was significantly higher in bacteremia cases resulting from ESBL-positive pathogens but also in K. pneumoniae cases disregarding ESBL-production. In order to examine whether pathogen species rather than multidrug resistance might affect mortality risk, we reanalyzed our dataset that includes 1.851 cases of bacteremia.

KeywordsESBL Bacteremia Sepsis K. pneumoniae E. coli Enterobacteriaceae Mortality AbbreviationsBSIBloodstream infections

E. coliEscherichia coli

ESBL-EExtended-spectrum beta-lactamase producing Enterobacteriaceae

HRHazard ratio

IQRInterquartile range

K. pneumoniaeKlebsiella pneumoniae

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Author: R. Leistner - A. Bloch - P. Gastmeier - F. Schwab

Source: https://link.springer.com/







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