Practice patterns among thyroid cancer surgeons: implications of performing a prophylactic central neck dissectionReportar como inadecuado




Practice patterns among thyroid cancer surgeons: implications of performing a prophylactic central neck dissection - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Journal of Otolaryngology - Head and Neck Surgery

, 45:55

First Online: 28 October 2016Received: 27 August 2016Accepted: 24 October 2016

Abstract

BackgroundIndications for performing a prophylactic central neck dissection pCND in papillary thyroid cancer PTC remain controversial. It is unclear how identification of lymph node LN metastases should impact the decision to treat with radioactive iodine RAI. The goals of this study were to identify indications for performing pCND and identify factors that predict the use of adjuvant RAI.

MethodsThis was a population based cross-sectional analysis. A prospectively collected database identified 594 patients who underwent total thyroidectomy +-− CND. A multivariate model was constructed to identify indications for pCND and predictors of the use of RAI.

Results425 CNDs were performed of which 224 were prophylactic. Conventional risk factors age, tumor size, extra-thyroidal extension were not associated with performing a pCND. The presence of clinically suspicious lymphadenopathy was the only factor associated with performing CND, thus rendering the CND therapeutic. Positive LNs were retrieved in 39 % of pCND’s, upstaging 87 patients. Among all peri-operative predictors of receiving RAI, presence of LN metastases was the strongest predictor OR = 5.9 3.7–9.5, while tumor size was a modest predictor OR = 1.8 1.5–2.1. Other conventional risk factors did not predict use of adjuvant RAI.

ConclusionsConventional risk factors were not indications for performing a pCND, implying that the decision was based on individual surgeon preference. Performing pCND upstaged 39 % of patients from cN0 to pN1a, increasing the likelihood of receiving RAI 6-fold. Conventional risk factors were not predictors of receiving adjuvant RAI. This highlights the need for a unified approach to performing a pCND and administering RAI.

KeywordsThyroid cancer Central neck dissection Radioactive iodine Epidemiology Lymph node metastasis Presentations: Presented at the 2nd World Congress on Thyroid Cancer in Toronto, Ontario, Canada, July 10–14, 2013

Download fulltext PDF



Autor: Michael W. Deutschmann - Laura Chin-Lenn - Steven C. Nakoneshny - Joseph C. Dort - Janice L. Pasieka - Shamir P. Chanda

Fuente: https://link.springer.com/







Documentos relacionados