Inclusion-body myositis: a difficult diagnosis? Reportar como inadecuado




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Maria Clara de Oliveira Magalhães ; Pedro Lucas de Mendonça Barbosa ; Eliene Dutra Campos ; Edmar Zanoteli ;Jornal Brasileiro de Patologia e Medicina Laboratorial 2014, 50 5

Autor: Carolina da Cunha Correia

Fuente: http://www.redalyc.org/articulo.oa?id=393541984008


Introducción



Jornal Brasileiro de Patologia e Medicina Laboratorial ISSN: 1676-2444 jbpml@sbpc.org.br,adagmar.andriolo@g mail.com Sociedade Brasileira de Patologia Clínica-Medicina Laboratorial Brasil da Cunha Correia, Carolina; de Oliveira Magalhães, Maria Clara; de Mendonça Barbosa, Pedro Lucas; Dutra Campos, Eliene; Zanoteli, Edmar Inclusion-body myositis: a difficult diagnosis? Jornal Brasileiro de Patologia e Medicina Laboratorial, vol.
50, núm.
5, septiembreoctubre, 2014, pp.
364-366 Sociedade Brasileira de Patologia Clínica-Medicina Laboratorial Rio de Janeiro, Brasil Available in: http:--www.redalyc.org-articulo.oa?id=393541984008 How to cite Complete issue More information about this article Journals homepage in redalyc.org Scientific Information System Network of Scientific Journals from Latin America, the Caribbean, Spain and Portugal Non-profit academic project, developed under the open access initiative case report Inclusion-body myositis: a difficult diagnosis? Miosite por corpos de inclusão: um diagnóstico difícil? Carolina da Cunha Correia1; Maria Clara de Oliveira Magalhães2; Pedro Lucas de Mendonça Barbosa2; Eliene Dutra Campos3; Edmar Zanoteli4 abstract Sporadic inclusion-body myositis (IBM) is the most common myopathy in individuals over 55 years of age.
However, in many cases, the diagnosis is neglected.
Its main findings include progressive muscle weakness, normal or low levels of serum creatine kinase, and the absence of a response to immunosuppression.
Muscle biopsy shows inflammatory reaction in association with degenerative changes of the muscle fibers.
We report a typical case of IBM, in which diagnosis was possible only after three muscle biopsies.
The challenges to confirm histological diagnosis and the caution to avoid repeating tests are discussed. Key words: skeletal muscle; myositis; muscular diseases; biopsy; muscle weakness. Introduction Idiopathic inflammatory myositis is a group of acquired and heterogeneous muscle illnesse...





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