Exclusive breastfeeding among women taking HAART for PMTCT of HIV-1 in the Kisumu Breastfeeding StudyReportar como inadecuado

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BMC Pediatrics

, 14:280

Nutrition, diet, physical health and endocrinology


BackgroundOne of the most effective ways to promote the prevention of mother-to-child transmission PMTCT of HIV-1 in resource-limited settings is to encourage HIV-positive mothers to practice exclusive breastfeeding EBF for the first 6 months post-partum while they receive antiretroviral therapy ARV. Although EBF reduces mortality in this context, its practice has been low. We studied the rate of adherence to EBF and assessed associated maternal and infant characteristics using data from a phase II PMTCT clinical trial conducted in Western Kenya which included a counseling intervention to encourage EBF by all participants.

MethodsWe analyzed data from the Kisumu Breastfeeding Study KiBS, conducted between July 2003 and February 2009. This study enrolled a total of 522 HIV-1 infected pregnant women. Data on breastfeeding were available for 480 mother-infant pairs. Infant feeding and general nutrition counseling began at 35 weeks gestation and continued throughout the 6 month post-partum intervention period, following World Health Organization WHO infant feeding guidelines. Data on infant feeding were collected during routine clinic visits and home visits using food frequency questionnaires and dietary recall methods. Participants were instructed to exclusively breastfeed until initiation of weaning at 5.5 months post-partum. We used Kaplan-Meier methods to estimate the rates of EBF at 5.25 months post-partum, stratified by maternal and infant characteristics measured at enrollment, delivery, and 2 weeks post-partum.

ResultsThe estimated EBF rate at 5.25 months post-partum was 80.4%. Only 3% of women introduced other foods most commonly water with or without glucose, cow’s milk, formula, and fruit by 2 months; this percentage increased to 5% of women by 4 months. Women who had ≥3 previous births p < 0.01 and who were not living with the infant’s father p = 0.04 were more likely to exclusively breastfeed. Mixed feeding was more common for male infants than for female infants p = 0.04.

ConclusionExclusive breastfeeding was common in this clinical trial, which emphasized EBF as a best practice until infants reached 5.5 months of age. Counseling initiated prior to delivery and continued during the post-partum period provided a consistent message reinforcing the benefits of EBF. The findings from this study suggest high adherence to EBF in resource limited settings can be achieved by a comprehensive counseling intervention that encourages EBF.

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Autor: John O Okanda - Craig B Borkowf - Sonali Girde - Timothy K Thomas - Shirley Lee Lecher

Fuente: https://link.springer.com/

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