The prevalence of the metabolically healthy obese phenotype in an aging population and its association with subclinical cardiovascular disease: The Brazilian study on healthy agingReportar como inadecuado




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Diabetology and Metabolic Syndrome

, 6:121

First Online: 07 November 2014Received: 24 April 2014Accepted: 29 October 2014

Abstract

BackgroundCurrent literature has elucidated a new phenotype, metabolically healthy obese MHO, with risks of cardiovascular disease similar to that of normal weight individuals. Few studies have examined the MHO phenotype in an aging population, especially in association with subclinical CVD.

Research design and methodsThis cross sectional study population consisted of 208 octogenarians and older. Anthropometrics, biochemical, and radiological parameters were measured to assess obesity, metabolic health assessed by the National Cholesterol Education Program –Adult Treatment Panel NCEP-ATP III criteria, and subclinical measures of CVD.

ResultsThe prevalence of MHO was 13.5% N = 28. No significant association with MHO was noted for age, coronary artery calcium score, cIMT, or hs-CRP > 3 mg-dl p = NS.

ConclusionsOur results suggest that the MHO phenotype exists in the elderly; however, subclinical CVD measures were not different in sub-group analysis suggesting traditional metabolic risk factor algorithms may not be accurate in the very elderly.

KeywordsObesity Aging Metabolic Syndrome Subclinical CVD  Download fulltext PDF



Autor: Lara Roberson - Sameer Shaharyar - Ehimen Aneni - Wladimir Freitas - Michael Blaha - Arthur Agatston - Roger Blumenthal - R

Fuente: https://link.springer.com/







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