IgG4-related systemic disease mimicking renal pelvic cancer: a rare caseReportar como inadecuado




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World Journal of Surgical Oncology

, 12:395

First Online: 23 December 2014Received: 27 August 2014Accepted: 03 December 2014

Abstract

BackgroundImmunoglobulin G4–related disease IgG4-RD is a new clinical entity. Characteristic features of IgG4-RD are elevated serum IgG4 levels, infiltration of IgG4-positive cells, mass-forming lesions with fibrosis and good response to corticosteroids. The variable imaging features of IgG4-RD and the overlap with other differential diagnoses often pose a diagnostic challenge, as they frequently mimic malignant tumors or other inflammatory diseases in the abdomen.

Case presentationA 54-year-old woman visited our hospital with left flank discomfort and palpebral edema. Computed tomography, magnetic resonance imaging, retrograde pyelography and positron emission tomography-computed tomography indicated renal pelvic cancer. However, after a left-sided nephroureteral cystectomy was performed, the mass was pathologically confirmed as an IgG4-related lesion. Her elevated serum IgG4 level and a past history of sicca complex supported the diagnosis of IgG4-RD.

ConclusionsIt is critical to recognize the importance of laboratory examinations such as serum IgG4 level if a patient has a past history of rheumatic disease.

KeywordsIgG4 Mikulicz’s disease Renal pelvic cancer Electronic supplementary materialThe online version of this article doi:10.1186-1477-7819-12-395 contains supplementary material, which is available to authorized users.

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Autor: Yiwei Wang - Xing Chen - Rongkui Luo - Hang Wang - Guomin Wang - Yingyong Hou - Jianming Guo

Fuente: https://link.springer.com/







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