Preference for wine is associated with lower hip fracture incidence in post-menopausal womenReportar como inadecuado

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BMC Women-s Health

, 13:36

Women-s health behaviors and health promotion health behaviors and health promotion


BackgroundPast studies of relationships between alcohol and hip fracture have generally focused on total alcohol consumed and not type of alcohol. Different types of alcohol consist of varying components which may affect risk of hip fracture differentially. This study seeks to examine the relationship between alcohol consumption, with a focus on type of alcohol consumed e.g. beer, wine, or hard liquor and hip fracture risk in post-menopausal women.

MethodsThe longitudinal cohort consisted of U.S. post-menopausal women aged 50–79 years enrolled between 1993–1998 in the Women’s Health Initiative Clinical Trials and Observational Study N=115,655.

ResultsWomen were categorized as non-drinkers, past drinkers, infrequent drinkers and drinkers by preference of alcohol type i.e. those who preferred wine, beer, hard liquor, or who had no strong preference. Mean alcohol consumption among current drinkers was 3.3 servings per week; this was similar among those who preferred wine, beer and liquor. After adjustment for potential confounders, alcohol preference was strongly correlated with hip fracture risk p = 0.0167; in particular, women who preferred wine were at lower risk than non-drinkers OR=0.78; 95% CI 0.64-0.95, past drinkers OR=0.85; 95% CI 0.72-1.00, infrequent drinkers OR=0.73; 95% CI 0.61-0.88, hard liquor drinkers OR=0.87; 95% CI 0.71-1.06, beer drinkers OR=0.72; 95% CI 0.55-0.95 and those with no strong preference OR=0.89; 95% CI 0.89; 95% CI 0.73-1.10.

ConclusionsPreference of alcohol type was associated with hip fracture; women who preferentially consumed wine had a lower risk of hip fracture compared to non-drinkers, past drinkers, and those with other alcohol preferences.

KeywordsAlcohol Wine Hip fracture Osteoporosis Women’s Health Initiative AbbreviationsWHIWomen’s Health Initiative

CTClinical Trial

OSObservational Study

FFQFood Frequency Questionnaire

BMDBone mineral density

HTHormone Therapy.

Electronic supplementary materialThe online version of this article doi:10.1186-1472-6874-13-36 contains supplementary material, which is available to authorized users.

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Autor: Jessica T Kubo - Marcia L Stefanick - John Robbins - Jean Wactawski-Wende - Mark R Cullen - Matthew Freiberg - Manisha D


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