Penile metastasis from primary cholangiocarcinoma: the first case reportReportar como inadecuado

Penile metastasis from primary cholangiocarcinoma: the first case report - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

BMC Gastroenterology

, 13:149

Hepatobiliary and pancreatic disorders


BackgroundMetastatic penile carcinoma derived from cholangiocarcinoma CCA has not been previously reported in the literature. Common metastatic sites for CCA include the regional lymph nodes and adjacent organs. CCAs are not highly vascularised tumours, making hematogenous metastases uncommon. Hematogenous CCA metastases commonly occur at distant organs such as the lungs, adrenal glands, and bones. Median survival for patients with metastatic disease is generally less than 1 year.

Case presentationA 74-year-old Caucasian man consulted us after having undergone penile ultrasonography for pain and increased thickness at the base of the penis after self-examination. The patient presented with a history of hepatitis C-related cirrhosis and intrahepatic CCA, diagnosed 3 years previously. A biopsy of the corpora cavernosa on both sides revealed a carcinoma harbouring the same histological and immunophenotypical features as the primary hepatic lesion.

ConclusionsTo date, there is no case of penile or urogenital system metastasis from CCA described in the literature. Therefore, this article represents the first case report of penile metastasis from CCA.

KeywordsCholangiocarcinoma Elastography Magnetic resonance Penile metastases AbbreviationsCCACholangiocarcinoma

CEACarcinoembryonic antigen

EMAEpithelial membrane antigen

MRIMagnetic resonance imaging.

Electronic supplementary materialThe online version of this article doi:10.1186-1471-230X-13-149 contains supplementary material, which is available to authorized users.

Download fulltext PDF

Autor: Antonio Luigi Pastore - Giovanni Palleschi - Giorgia Manfredonia - Piero Maceroni - Domenico Alvaro - Domenico De Santis -


Documentos relacionados