An improved survivability prognosis of breast cancer by using sampling and feature selection technique to solve imbalanced patient classification dataReportar como inadecuado




An improved survivability prognosis of breast cancer by using sampling and feature selection technique to solve imbalanced patient classification data - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

BMC Medical Informatics and Decision Making

, 13:124

Standards, technology, and modeling

Abstract

BackgroundBreast cancer is one of the most critical cancers and is a major cause of cancer death among women. It is essential to know the survivability of the patients in order to ease the decision making process regarding medical treatment and financial preparation. Recently, the breast cancer data sets have been imbalanced i.e., the number of survival patients outnumbers the number of non-survival patients whereas the standard classifiers are not applicable for the imbalanced data sets. The methods to improve survivability prognosis of breast cancer need for study.

MethodsTwo well-known five-year prognosis models-classifiers i.e., logistic regression LR and decision tree DT are constructed by combining synthetic minority over-sampling technique SMOTE ,cost-sensitive classifier technique CSC, under-sampling, bagging, and boosting. The feature selection method is used to select relevant variables, while the pruning technique is applied to obtain low information-burden models. These methods are applied on data obtained from the Surveillance, Epidemiology, and End Results database. The improvements of survivability prognosis of breast cancer are investigated based on the experimental results.

ResultsExperimental results confirm that the DT and LR models combined with SMOTE, CSC, and under-sampling generate higher predictive performance consecutively than the original ones. Most of the time, DT and LR models combined with SMOTE and CSC use less informative burden-features when a feature selection method and a pruning technique are applied.

ConclusionsLR is found to have better statistical power than DT in predicting five-year survivability. CSC is superior to SMOTE, under-sampling, bagging, and boosting to improve the prognostic performance of DT and LR.

KeywordsBreast cancer Decision tree Logistic regression Imbalanced data Synthetic minority over-sampling Cost-sensitive classifier technique Electronic supplementary materialThe online version of this article doi:10.1186-1472-6947-13-124 contains supplementary material, which is available to authorized users.

Kung-Jeng Wang, Bunjira Makond contributed equally to this work.

Download fulltext PDF



Autor: Kung-Jeng Wang - Bunjira Makond - Kung-Min Wang

Fuente: https://link.springer.com/







Documentos relacionados