Botulinum toxin treatment of salivary fistulas following parotidectomy: follow-up resultsReport as inadecuate

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Oral and Maxillofacial Surgery

, Volume 17, Issue 4, pp 281–285

First Online: 24 November 2012Received: 16 September 2012Accepted: 12 November 2012


BackgroundSalivary fistulas are a well-known sequel of parotidectomy, and successful treatment with botulinum toxin has been demonstrated in individual cases. Here, we report on 12 patients with fistulas treated following parotidectomy for various indications.

Methods and resultsInjection of botulinum toxin type A into the residual gland tissue was the initial treatment. After early intervention within 6 weeks after development of the fistula, only one fistula remained 9 of 10 fistulas treated early only with botulinum toxin. One patient with early intervention did not want to wait for the botulinum toxin treatment to take effect and demanded early surgical revision, which was successful. In one patient with a permanent fistula, botulinum toxin treatment began 420 days after the operation and was unsuccessful. No side effects were evident after the treatment.

ConclusionIn summary, botulinum toxin injections into the parotid tissue remaining after surgery appear to be an effective treatment for salivary fistulas following parotidectomy.

KeywordsParotidectomy Salivary fistulas Botulinum toxin Long-term results  Download fulltext PDF

Author: Rainer Laskawi - Jan Winterhoff - Sabrina Köhler - Laura Kottwitz - Christoph Matthias


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