Effect of Topical Loteprednol on Intraocular Pressure After Selective Laser Trabeculoplasty for Open-Angle GlaucomaReportar como inadecuado




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Ophthalmology and Therapy

, Volume 2, Issue 2, pp 113–120

First Online: 31 August 2013Received: 27 May 2013

Abstract

IntroductionTo determine whether there is a statistically significant difference in the decrease in intraocular pressure IOP after selective laser trabeculoplasty SLT between patients receiving a 5–7 days co-administration of loteprednol versus no loteprednol over the course of 1 year.

MethodsWe conducted a retrospective chart review to evaluate use of loteprednol in patients aged 30–85 years undergoing SLT for open-angle glaucoma at our center over a 3-year period.

ResultsThree hundred and eighteen eyes from 313 patients who underwent a 360° SLT treatment between January 2008 and August 2011 were included in the analysis. Patients who received loteprednol showed a mean reduction of 2.5 ±SE 0.3 mmHg or 11.8% ±1.5% in IOP versus a mean reduction of 3.2 ±0.6 mmHg or 14.9% ±2.5% in those not treated with loteprednol. This difference showed a trend toward lower IOP without loteprednol, but this was not statistically significant p = 0.29.

ConclusionPostoperative use of loteprednol does not appear to significantly affect IOP in patients undergoing SLT. A randomized double-blinded study in a larger group of patients would be required to clarify this issue. Until such information is available, we recommend that individual clinical judgment be used regarding whether to use topical steroids in patients undergoing SLT.

KeywordsGlaucoma Intraocular pressure Loteprednol Ophthalmology Selective laser trabeculoplasty Trabeculoplasty  Download fulltext PDF



Autor: Ronald L. Rebenitsch - Eric N. Brown - Nick R. Binder - Aditi Jani - Aaron J. Bonham - Rohit Krishna - Kevin Pikey

Fuente: https://link.springer.com/







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