Magnetite nanoparticles for functionalized textile dressing to prevent fungal biofilms developmentReportar como inadecuado

Magnetite nanoparticles for functionalized textile dressing to prevent fungal biofilms development - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Nanoscale Research Letters

, 7:501

First Online: 06 September 2012Received: 19 May 2012Accepted: 01 September 2012


The purpose of this work was to investigate the potential of functionalized magnetite nanoparticles to improve the antibiofilm properties of textile dressing, tested in vitro against monospecific Candida albicans biofilms. Functionalized magnetite Fe3O4-C18, with an average size not exceeding 20 nm, has been synthesized by precipitation of ferric and ferrous salts in aqueous solution of oleic acid C18 and NaOH. Transmission electron microscopy, X-ray diffraction analysis, and differential thermal analysis coupled with thermo gravimetric analysis were used as characterization methods for the synthesized Fe3O4-C18. Scanning electron microscopy was used to study the architecture of the fungal biofilm developed on the functionalized textile dressing samples and culture-based methods for the quantitative assay of the biofilm-embedded yeast cells. The optimized textile dressing samples proved to be more resistant to C. albicans colonization, as compared to the uncoated ones; these functionalized surfaces-based approaches are very useful in the prevention of wound microbial contamination and subsequent biofilm development on viable tissues or implanted devices.

Electronic supplementary materialThe online version of this article doi:10.1186-1556-276X-7-501 contains supplementary material, which is available to authorized users.

Download fulltext PDF

Autor: Ion Anghel - Alexandru Mihai Grumezescu - Ecaterina Andronescu - Alina Georgiana Anghel - Anton Ficai - Crina Saviuc - Val


Documentos relacionados