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Microbial Cell Factories

, 11:129

First Online: 14 September 2012Received: 13 September 2012Accepted: 13 September 2012

Abstract

The production of heterologous disulfide bonded proteins in bacteria remains a biotechnological challenge. A rapid literature survey results in the identification of some interesting proposals, such as the option of producing functional proteins in the cytoplasm in the presence of sulfhydryl oxidases and isomerases. Furthermore, an ever-increasing number of applications refers to recombinant proteins displayed at the bacterial surface. Time will tell whether these developments will lead to universally accepted laboratory protocols.

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Autor: Ario de Marco

Fuente: https://link.springer.com/



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