Primary yolk sac tumor of seminal vesicle: a case report and literature reviewReportar como inadecuado

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World Journal of Surgical Oncology

, 10:189

First Online: 14 September 2012Received: 12 June 2012Accepted: 11 August 2012


BackgroundYolk sac tumor endodermal sinus tumor is a rare malignant germ cell tumor arising in the testis or ovary. Extragonadal yolk sac tumor is even rarer and has only been described in case reports. Due to the rarity of the tumors, the appropriately optimal treatment remains unclear. We report a case of yolk sac tumor in the seminal vesicle.

CaseA 38-year-old Asian male presented with gross hematuria and hemospermia. Transrectal ultrasound scan showed a solid mass in the left seminal vesicle and the scrotal sonography showed no abnormalities. Bilateral seminal vesicles were resected, and histopathological examination showed a typical pattern of yolk sac tumor YST. The patient responded poorly to comprehensive treatment of radiotherapy, chemotherapy and surgeries, developed systemic multiple metastases, and died of cachexia one and half years after diagnosis.

KeywordsYolk sac tumor Seminal vesicle Extragonadal AbbreviationsYSTyolk sac tumor


CTcomputed tomography

MRImagnetic resonance imaging

PSAprostate-specific antigen

PET-CTPositron emission tomography-computed tomography

GCTgerm cell tumor

EGCTextragonadal germ cell tumor

NSEGCTnonseminomatous extragonadal germ cell tumor.

Electronic supplementary materialThe online version of this article doi:10.1186-1477-7819-10-189 contains supplementary material, which is available to authorized users.

Xu-Dong Yao, Ya-Ping Hong contributed equally to this work.

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Autor: Xu-Dong Yao - Ya-Ping Hong - Ding-Wei Ye - Chao-Fu Wang


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