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1 LGC - Laboratoire de génie chimique 2 INSERM - Institut National de la Santé et de la Recherche Médicale 3 Università della Calabria ITALIA

Abstract : Chylothorax is an uncommon form of pleural effusion, which generally occurs after cardiac surgery and almost any surgical operation in the chest. The aim of this project is to develop a bioresorbable vascular patch for lymphatic wall repair 1. Here, we project to develop new materials i.e. membranes having two different levels of porosity 2. First short tests made with Polycaprolactone PCL membranes and PCL was blended with different biocompatible, bioresorbable membranes. It shows that human dermal lymphatic endothelial HDLEC cells can bind and spread on certain membrane and not on others suggesting that the chemical structure and the morphology of the membranes is important.

Keywords : Artificial membrane Double porosity Chylothorax

Autor: Pritam Das - Jean-Francois Lahitte - Jean-Christophe Remigy - Barbara Garmy-Susini - Sandrine Desclaux - Clémence Coetsier - Lor



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