Magnetic liquid marbles, their manipulation and application in optical probingReport as inadecuate

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Microfluidics and Nanofluidics

, Volume 13, Issue 4, pp 555–564

First Online: 10 April 2012Received: 14 February 2012Accepted: 27 March 2012


Magnetic liquid marbles, an encapsulation of liquid droplet with hydrophobic magnetic particles, show remarkable responsiveness to external magnetic force and great potential to be used as a discrete droplet microfluidic system. In this study, we presented the manipulation of a magnetic liquid marble under an external magnetic field and calculated the maximum frictional force, the magnetic force required for actuating the liquid marbles and the effective surface tension of the magnetic liquid marble, as well as the threshold volume for the transition from quasi-spherical to puddle-like shape. By taking advantage of the unique feature of being opened and closed reversibly, we have proven the encapsulated droplets can be detected optically with a reflection-mode probe. Combining the open-close and optical detection also enables to probe chemical reactions taking place within liquid marbles. These remarkable features offer a simple yet powerful alternative to conventional discrete microfluidic systems and may have wide applications in biomedical and drug discovery.

KeywordsLiquid marble Microfluidics Magnetic nanoparticle Microreactor Droplet  Download fulltext PDF

Author: Yan Zhao - Zhiguang Xu - Marzieh Parhizkar - Jian Fang - Xungai Wang - Tong Lin


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