Cytogenetic aberrations in primary cell cultures of the ovarian surface epithelium. Report as inadecuate




Cytogenetic aberrations in primary cell cultures of the ovarian surface epithelium. - Download this document for free, or read online. Document in PDF available to download.

Sandra Rondón-Lagos ; Amparo Ramírez-Corredor ; Milcíade Ibáñez-Pinilla ; Sandra Ramírez-Clavijo ;Investigación Clínica 2010, 51 4

Author: Lilian Chuaire-Noack

Source: http://www.redalyc.org/articulo.oa?id=372937682010


Teaser



Investigación Clínica ISSN: 0535-5133 riclinicas@gmail.com Universidad del Zulia Venezuela Chuaire-Noack, Lilian; Rondón-Lagos, Sandra; Ramírez-Corredor, Amparo; Ibáñez-Pinilla, Milcíade; Ramírez-Clavijo, Sandra Cytogenetic aberrations in primary cell cultures of the ovarian surface epithelium. Investigación Clínica, vol.
51, núm.
4, 2010, pp.
541-551 Universidad del Zulia Maracaibo, Venezuela Available in: http:--www.redalyc.org-articulo.oa?id=372937682010 How to cite Complete issue More information about this article Journals homepage in redalyc.org Scientific Information System Network of Scientific Journals from Latin America, the Caribbean, Spain and Portugal Non-profit academic project, developed under the open access initiative Invest Clin 51(4): 541 - 551, 2010 Cytogenetic aberrations in primary cell cultures of the ovarian surface epithelium. Lilian Chuaire-Noack1, Sandra Rondón-Lagos1, Amparo Ramírez-Corredor2, Milcíades Ibáñez-Pinilla3, Sandra Ramírez-Clavijo1. Laboratorio de Biología Celular y Molecular, Facultad de Ciencias Naturales y Matemáticas, Universidad del Rosario, 2Hospital Occidente de Kennedy y 3Facultad de Medicina y Ciencias de la Salud, Universidad del Rosario.
Bogotá DC, Colombia. 1 Key words: cell cultures, chromosome aberrations, chromosomal instability, ovarian epithelium, polyploidy. Abstract.
Our objective was to determine the presence of chromosomal abnormalities in primary cultures of ovarian surface epithelial cells in women of different ages with no history of cancer.
Throughout conventional cytogenetic techniques, we analyzed chromosome spreads of cultured ovarian epithelial cells from 10 donors who were 50 or more years old (B) and 16 controls between 20 and 49 years old (A), belonging to the mestizo population in Bogota DC, Colombia.
Of the 26 cultures that were analyzed in passage 1, 61.5% had an abnormal chromosome complement (62.5% in A, and 60% in B). Abnormalities included polyploidies, endod...





Related documents