I-131-Metaiodobenzylguanidine therapy with allogeneic cord blood stem cell transplantation for recurrent neuroblastomaReportar como inadecuado




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Italian Journal of Pediatrics

, 38:53

First Online: 15 October 2012Received: 07 July 2012Accepted: 11 October 2012

Abstract

Iodine-131-metaiodiobenzylguanidine I-MIBG therapy combined with allogeneic cord blood stem cell transplantation SCT was used to treat a 4-year-old girl with recurrent neuroblastoma. The patient experienced relapse 2 years after receiving first-line therapies, which included chemotherapy, surgical resection, irradiation, and autologous peripheral SCT. Although I-MIBG treatment did not achieve complete remission, the size of the tumor was reduced after treatment. Based on our findings, we suggest that I-MIBG treatment with myeloablative allogeneic SCT should be considered as first-line therapy for high-risk neuroblastoma patients when possible.

KeywordsMIBG Neuroblastoma Allogeneic cord blood stem cell transplantation Electronic supplementary materialThe online version of this article doi:10.1186-1824-7288-38-53 contains supplementary material, which is available to authorized users.

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Autor: Yuya Sato - Hidemitsu Kurosawa - Keitaro Fukushima - Mayuko Okuya - Susumu Hagisawa - Kenichi Sugita - Osamu Arisaka - Anri

Fuente: https://link.springer.com/







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