Size-dependent antimicrobial properties of sugar-encapsulated gold nanoparticles synthesized by a green methodReportar como inadecuado




Size-dependent antimicrobial properties of sugar-encapsulated gold nanoparticles synthesized by a green method - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Nanoscale Research Letters

, 7:623

First Online: 12 November 2012Received: 06 August 2012Accepted: 31 October 2012

Abstract

The antimicrobial properties of dextrose-encapsulated gold nanoparticles dGNPs with average diameters of 25, 60, and 120 nm ± 5 and synthesized by green chemistry principles were investigated against both Gram-negative and Gram-positive bacteria. Studies were performed involving the effect of dGNPs on the growth, morphology, and ultrastructural properties of bacteria. dGNPs were found to have significant dose-dependent antibacterial activity which was also proportional to their size. Experiments revealed the dGNPs to be bacteriostatic as well as bactericidal. The dGNPs exhibited their bactericidal action by disrupting the bacterial cell membrane which leads to the leakage of cytoplasmic content. The overall outcome of this study suggests that green-synthesized dGNPs hold promise as a potent antibacterial agent against a wide range of disease-causing bacteria by preventing and controlling possible infections or diseases.

KeywordsGold nanoparticles Green synthesis Antibacterial activity Propidium iodide Outer membrane vesicles Electronic supplementary materialThe online version of this article doi:10.1186-1556-276X-7-623 contains supplementary material, which is available to authorized users.

Vivek D Badwaik, Lakshmisri M Vangala contributed equally to this work.

Download fulltext PDF



Autor: Vivek D Badwaik - Lakshmisri M Vangala - Dillon S Pender - Chad B Willis - Zoraida P Aguilar - Matthew S Gonzalez - Ra

Fuente: https://link.springer.com/



DESCARGAR PDF




Documentos relacionados