Multicenter assessment of the reproducibility of volumetric radiofrequency-based intravascular ultrasound measurements in coronary lesions that were consecutively stentedReportar como inadecuado




Multicenter assessment of the reproducibility of volumetric radiofrequency-based intravascular ultrasound measurements in coronary lesions that were consecutively stented - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

The International Journal of Cardiovascular Imaging

, Volume 28, Issue 8, pp 1867–1878

First Online: 14 January 2012Received: 28 September 2011Accepted: 02 January 2012

Abstract

To assess in a multicenter design the between-center reproducibility of volumetric virtual histology intravascular ultrasound VH-IVUS measurements with a semi-automated, computer-assisted contour detection system in coronary lesions that were consecutively stented. To evaluate the reproducibility of volumetric VH-IVUS measurements, experienced analysts of 4 European IVUS centers performed independent analyses in total 8,052 cross-sectional analyses to obtain volumetric data of 40 coronary segments length 20.0 ± 0.3 mm from target lesions prior to percutaneous intervention that were performed in the setting of stable 65% or unstable angina pectoris 35%. Geometric and compositional VH-IVUS measurements were highly correlated for the different comparisons. Overall intraclass correlation for vessel, lumen, plaque volume and plaque burden was 0.99, 0.92, 0.96, and 0.83, respectively; for fibrous, fibro-lipidic, necrotic core and calcified volumes overall intraclass correlation was 0.96, 0.94, 0.98, and 0.99, respectively. Nevertheless, significant differences for both geometrical and compositional measurements were seen. Of the plaque components, fibrous tissue and necrotic core showed on average the highest measurement reproducibility. A central analysis for VH-IVUS multicenter studies of lesions prior to PCI should be pursued. Moreover, it may be problematical to pool VH-IVUS data of individual trials analyzed by independent centers.

KeywordsCoronary artery disease Intravascular ultrasound Radiofrequency Virtual Histology Measurement reproducibility Percutaneous coronary interventions AbbreviationsIVUSIntravascular ultrasound

VHVirtual histology

PCIPercutaneous coronary intervention

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Autor: Jennifer Huisman - Rasmus Egede - Adam Rdzanek - Dirk Böse - Raimund Erbel - Janusz Kochman - Lisette Okkels Jensen - Job

Fuente: https://link.springer.com/







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