Synthesis, structure, and tuberculostatic activity of dimethyl benzoylcarbonohydrazonodithioatesReport as inadecuate

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Monatshefte für Chemie - Chemical Monthly

, 142:1137

First Online: 16 August 2011Received: 23 September 2010Accepted: 12 July 2011

AbstractNew dimethyl benzoylcarbonohydrazonodithioates were obtained by CS2 addition to arylcarboxylic acid hydrazides and methylation of the formed adduct. The new derivatives were tested for their activity against Mycobacterium tuberculosis. Some compounds exhibited high activity toward sensitive and resistant strains.

Graphical abstractOpen image in new windowKeywordsBenzohydrazides Crystal structure Hydrogen bonds Tuberculostatic activity Structure–activity relationship  Download fulltext PDF

Author: Katarzyna Gobis - Henryk Foks - Zofia Zwolska - Ewa Augustynowicz-Kopeć - Marek L. Główka - Andrzej Olczak - Michał Sa


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