Synthesis of new 6-halogeno-imidazo1,2-apyridines by SRN1 reactionsReportar como inadecuado




Synthesis of new 6-halogeno-imidazo1,2-apyridines by SRN1 reactions - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

* Corresponding author 1 CBRL - Chimie, biologie et radicaux libres - UMR 6517 2 ICR - Institut de Chimie Radicalaire

Abstract : New 2-chloromethyl-6-halogeno-imidazo1,2-apyridines and 2-chloromethyl-6-halogeno-3-nitroimidazo1,2-apyridines were prepared and reacted under experimental conditions of S RN 1 reactions with different sulfur and carbon centered nucleophiles to give new 6-halogeno-2-substituted-imidazo1,2-apyridines and 6-halogeno-3-nitro-2-substituted-imidazo1,2-a pyridines in good yields. Only the chloromethyl group was found to be reactive under these experimental conditions.

Keywords : SRN1 Imidazo1 2-apyridine reductive alkylating agent nitroheterocycles





Autor: Maxime D. Crozet - Caroline Castera - Mustapha Kaafarani - Michel Crozet Patrice Vanelle -

Fuente: https://hal.archives-ouvertes.fr/



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