Health-related quality of life in adults reporting arthritis: analysis from the National Health Measurement StudyReportar como inadecuado

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Quality of Life Research

, Volume 20, Issue 7, pp 1131–1140

First Online: 05 February 2011Accepted: 13 January 2011


BackgroundArthritis is the leading cause of disability in the United States. We assess the generic health-related quality-of-life HRQOL among a nationally representative sample of US adults with and without self-reported arthritis.

MethodsThe NHMS, a cross-sectional survey of 3,844 adults 35–89 years administered EuroQol-5D EQ-5D, Health Utilities Index Mark 2 HUI2 and 3 HUI3, SF-36v2™, Quality of Well-being Scale self-administered form QWB-SA, and the Health and Activities Limitations index HALex to each respondent via a telephone interview. Weighted multiple linear regression was used to generate age-gender-arthritis-stratified unadjusted HRQOL means and means adjusted for sociodemographic, socioeconomic covariates and comorbidities by arthritis–age category.

ResultsThe estimated population prevalence of self-reported arthritis was 31%. People with arthritis were more likely to be woman, older, of lower socioeconomic status, and had more self-reported comorbidities than were those not reporting arthritis. Adults with arthritis had lower HRQOL on six different indexes compared with adults without arthritis, with overall differences ranging from 0.03 QWB-SA, age-group 65–74 to 0.17 HUI3, age-group 35–44; all P-value < .05.

ConclusionArthritis in adults is associated with poorer HRQOL. We provide age-related reference values for six generic HRQOL measures in people with arthritis.

KeywordsHealth-Related Quality of Life HRQOL Arthritis National Health Measurement Study Self-reported arthritis EQ-5D SF-6D HUI2 HUI3 HALex QWB QWB-SA  Download fulltext PDF

Autor: Dinesh Khanna - Paul Maranian - Mari Palta - Robert M. Kaplan - Ron D. Hays - Dasha Cherepanov - Dennis G. Fryback


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