Effect of ketogenic mediterranean diet with phytoextracts and low carbohydrates-high-protein meals on weight, cardiovascular risk factors, body composition and diet compliance in Italian council employeesReportar como inadecuado




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Nutrition Journal

, 10:112

First Online: 12 October 2011Received: 13 July 2011Accepted: 12 October 2011

Abstract

BackgroundThere has been increased interest in recent years in very low carbohydrate ketogenic diets VLCKD that, even though they are much discussed and often opposed, have undoubtedly been shown to be effective, at least in the short to medium term, as a tool to tackle obesity, hyperlipidemia and some cardiovascular risk factors. For this reason the ketogenic diet represents an interesting option but unfortunately suffers from a low compliance. The aim of this pilot study is to ascertain the safety and effects of a modified ketogenic diet that utilizes ingredients which are low in carbohydrates but are formulated to simulate its aspect and taste and also contain phytoextracts to add beneficial effects of important vegetable components.

MethodsThe study group consisted of 106 Rome council employees with a body mass index of ≥ 25, age between 18 and 65 years 19 male and 87 female; mean age 48.49 ± 10.3. We investigated the effects of a modified ketogenic diet based on green vegetables, olive oil, fish and meat plus dishes composed of high quality protein and virtually zero carbohydrate but which mimic their taste, with the addition of some herbal extracts KEMEPHY ketogenic Mediterranean with phytoextracts. Calories in the diet were unlimited. Measurements were taken before and after 6 weeks of diet.

ResultsThere were no significant changes in BUN, ALT, AST, GGT and blood creatinine. We detected a significant p < 0.0001 reduction in BMI 31.45 Kg-m to 29.01 Kg-m, body weight 86.15 kg to 79.43 Kg, percentage of fat mass 41.24% to 34.99%, waist circumference 106.56 cm to 97.10 cm, total cholesterol 204 mg-dl to 181 mg-dl, LDLc 150 mg-dl to 136 mg-dl, triglycerides 119 mg-dl to 93 mg-dl and blood glucose 96 mg-dl to 91 mg-dl. There was a significant p < 0.0001 increase in HDLc 46 mg-dl to 52 mg-dl.

ConclusionsThe KEMEPHY diet lead to weight reduction, improvements in cardiovascular risk markers, reduction in waist circumference and showed good compliance.

AbbreviationsKEMEPHYketogenic Mediterranean with phytoextracts

VLCKDvery low carbohydrate ketogenic diet high-density lipoprotein cholesterol

LDLclow-density lipoprotein cholesterol

TGTriglycerides

GLUGlucose

BUNBlood Urea Nitrogen

UAUric acid

ALTAlanine aminotransferase

ASTAspartate Aminotransferase

GGTGamma-glutamyl transpeptidase

CrCreatinine.

Electronic supplementary materialThe online version of this article doi:10.1186-1475-2891-10-112 contains supplementary material, which is available to authorized users.

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Autor: Antonio Paoli - Lorenzo Cenci - Keith A Grimaldi

Fuente: https://link.springer.com/



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