Norsesquiterpenoids from the leaves of Croton tigliumReport as inadecuate

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Natural Products and Bioprospecting

, Volume 1, Issue 3, pp 134–137

First Online: 02 January 2012Received: 21 November 2011Accepted: 14 December 2011


Two new compounds, badounoids A 1 and B 2 , together with 13 known norsesquiterpenes, were isolated from the leaves of Croton tiglium L. The structures of the new compounds were established by means of spectroscopic methods. The absolute configuration of badounoid B was determined by single-crystal X-ray diffraction analysis. All the known compounds were isolated from Croton plants for the first time which added a new chemical facet for this genus. The selected compounds were evaluated for their cytostatic activity against several cancer cell lines. None of them was found to be active. Open image in new window

KeywordsCroton tiglium badounoid norsesquiterpenoid cytostatic activity These authors contributed equally to this work.

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Electronic Supplementary MaterialSupplementary material is available for this article at 10.1007-s13659-011-0035-3 and is accessible for authorized users.

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Author: Wei Bu - Yan-Ni Shi - Yong-Ming Yan - Qing Lu - Guang-Ming Liu - Yan Li - Yong-Xian Cheng


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