Structural and physical properties of antibacterial Ag-doped nano-hydroxyapatite synthesized at 100°CReportar como inadecuado




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Nanoscale Research Letters

, 6:613

First Online: 03 December 2011Received: 06 June 2011Accepted: 03 December 2011

Abstract

Synthesis of nanosized particle of Ag-doped hydroxyapatite with antibacterial properties is in the great interest in the development of new biomedical applications. In this article, we propose a method for synthesized the Ag-doped nanocrystalline hydroxyapatite. A silver-doped nanocrystalline hydroxyapatite was synthesized at 100°C in deionized water. Other phase or impurities were not observed. Silver-doped hydroxyapatite nanoparticles Ag:HAp were performed by setting the atomic ratio of Ag-Ag + Ca at 20% and Ca + Ag-P as 1.67. The X-ray diffraction studies demonstrate that powders made by co-precipitation at 100°C exhibit the apatite characteristics with good crystal structure and no new phase or impurity is found. The scanning electron microscopy SEM observations suggest that these materials present a little different morphology, which reveals a homogeneous aspect of the synthesized particles for all samples. The presence of calcium Ca, phosphor P, oxygen O, and silver Ag in the Ag:HAp is confirmed by energy dispersive X-ray EDAX analysis. FT-IR and FT-Raman spectroscopies revealed that the presence of the various vibrational modes corresponds to phosphates and hydroxyl groups. The strain of Staphylococcus aureus was used to evaluate the antibacterial activity of the Ca10-xAgxPO46OH2 x = 0 and 0.2. In vitro bacterial adhesion study indicated a significant difference between HAp x = 0 and Ag:HAp x = 0.2. The Ag:Hap nanopowder showed higher inhibition.

AbbreviationsEDAXenergy-dispersive X-ray spectroscopy

FT-IR spectroscopyFourier transform infrared spectroscopy

FT-Raman spectroscopyFourier transforms Raman spectroscopy

SEMscanning electron microscopy

TEMtransmission electron microscopy

XRDX-ray diffraction.

Electronic supplementary materialThe online version of this article doi:10.1186-1556-276X-6-613 contains supplementary material, which is available to authorized users.

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Autor: Carmen Steluta Ciobanu - Florian Massuyeau - Liliana Violeta Constantin - Daniela Predoi

Fuente: https://link.springer.com/







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