Lipid raft-based strategies to interfere with HIV-1 infection - VIH (Virus) - Tesis doctorales; Péptidos - Tesis doctoralesReportar como inadecuado




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Autor: Vieira, Catarina Reis

Tutores: Mañes Brotón, Santos (dir.)

Lugar: Universidad Autónoma de Madrid. Departamento de Biología Molecular

Fecha de publicación: 2009

Área: VIH (Virus) - Tesis doctorales; Péptidos - Tesis doctorales

Notas: Tesis doctoral inédita. Universidad Autónoma de Madrid, Facultad de Ciencias, Departamento de Biología Molecular. Fecha de lectura: 16-02-2009





Autor: Vieira, Catarina Reis

Fuente: https://repositorio.uam.es


Introducción



UNIVERSIDAD AUTÓNOMA DE MADRID FACULTAD DE CIENCIAS DEPARTAMENTO DE BIOLOGÍA MOLECULAR LIPID RAFT-BASED STRATEGIES TO INTERFERE WITH HIV-1 INFECTION TESIS DOCTORAL CATARINA REIS VIEIRA MADRID, DICIEMBRE 2008 The work presented in this thesis has been performed in the Department of Inmunology and Oncology of the National Center of Biotechnology (CSIC), under the supervision of Prof.
Dr.
Santos Mañes Brotón. Dedicated to Filipe INDEX -- INDEX List of abbreviations .13 List of Tables and Figures .19 Summary .23 Introduction .27 1.
The Human Immunodeficiency Virus Type I .29 1.1 AIDS - an emerging epidemic 1.2 Structure of the virus particle 1.3 Replication cycle overview 1.4 Current treatment options 2.
Mechanism of HIV-1 entry into target cells .34 2.1 Attachment to the CD4 receptor 2.2 Attachment to a chemokine co-receptor 2.3 Fusion of the membranes 2.4 The fusion inhibitor enfuvirtide 3.
Lipid rafts in the cell membrane .39 3.1 Structure and lipid composition 3.2 Protein composition 3.3 Function in the context of the cell 3.4 Role of lipid rafts in HIV-1 infection 3.5 Artefact or real? Objectives ....






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